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The Food and Drug Administration, FDA, has approved the drug Vivitrol for the treatment of opioid dependence in accordance with a news release by them on 10-12-2010.

Using two separate drugs to shed weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people that go through it one should err to the side of caution and allow FDA do its job and demand some study be done so the public is aware of the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to generate money and that they would say almost anything to keep people on his or her medications.

Researchers discovered that participants using this drug for any year, dropped excess weight within 4 weeks and have kept the extra weight off throughout the 56 weeks with the study. Contrave is often a combination in the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which can be made up of more than one active ingredient, that might make them more efficient and safer.

Combo-pilling may be the newest fad or also the newest ahead under scrutiny and therefore it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills has become popular may be the fact that by right now there are no long term prescription weightloss pills that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug may also raise hypertension and pulse rate, and shouldn't be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure level and heartbeat and must 't be used in patients with uncontrolled high blood pressure, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients for the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.

From a psychiatric standpoint, evidence shows that the ordinary neural mechanism for goal-directed behavior continues to be hijacked by the addiction, and malfunctions such that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus along with the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).